Jobs in San Francisco, CA
1,277 open roles — posted here, and found on employers' own careers sites.
Product Manager, Safeguards (Cyber)
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $305,000 – $385,000
This Product Manager role leads the design and deployment of safety systems for Anthropic's AI models across multiple platforms, working with research, engineering, and policy teams to detect and mitigate risks. The role suits experienced product managers who combine deep technical expertise in AI safety with the ability to prioritize ruthlessly, communicate complex concepts clearly, and navigate ambiguity in a rapidly evolving field.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Staff Software Engineer, Managed Orchestration (Managed Kubernetes)
Crusoe
Full-time · San Francisco, CA · $220,000 – $250,000
Crusoe is seeking a Staff Software Engineer to design and scale their Kubernetes orchestration infrastructure for AI workloads, working on system architecture, operators, and cloud platform reliability. This role suits experienced systems engineers who want to own critical infrastructure projects in a high-growth AI infrastructure company.
Listed on Crusoe’s careers site · Apply there ↗
Real Estate Portfolio Manager
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $275,000
Anthropic seeks an experienced leader to establish and manage a real estate strategy function for the AI research company's rapidly scaling global footprint. This role demands deep expertise in corporate real estate finance and market analysis, combined with executive communication skills and team leadership experience in fast-growth environments.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Enterprise Account Executive
Crusoe
Full-time · San Francisco, CA · $300,000 – $400,000
Crusoe is hiring an Enterprise Account Executive to build relationships with large enterprises and close high-value AI infrastructure deals. This role suits experienced cloud sales professionals who can navigate complex enterprise buying cycles and understand AI/ML workload requirements.
Listed on Crusoe’s careers site · Apply there ↗
Strategic Account Executive, Cybersecurity
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $380,000 – $450,000
This role sells Claude AI to cybersecurity vendors building AI-powered security products and services. You'll manage strategic accounts, navigate complex buying committees spanning product, engineering, and executive leadership, and drive multi-million dollar deals while collaborating with Anthropic's technical teams on custom deployments.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Senior Manager, Customer Support
Crusoe
Full-time · San Francisco, CA · $205,000 – $250,000
Crusoe is seeking an experienced technical leader to build and manage their customer support engineering team for a cutting-edge AI infrastructure platform. The role combines hands-on technical depth with people leadership, requiring someone who can solve complex cloud and GPU compute issues while coaching a growing team of support engineers.
Listed on Crusoe’s careers site · Apply there ↗
Research Economist, Economic Research
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $320,000 – $405,000
Anthropic is seeking an economist to research how artificial intelligence affects labor markets, productivity, and the broader economy. This role suits researchers with strong empirical methods experience who want to apply econometric and causal-inference techniques to understand AI's real-world economic impact.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Director, Commercial Operations
Crusoe
San Francisco, CA · $180,000 – $220,000
This director-level role leads the operational and analytical functions of Crusoe's Energy Development Group, building financial models and managing processes that evaluate large-scale power and data center opportunities. It suits someone with deep energy sector expertise and proven experience building high-performing analyst teams who wants to shape how a venture-backed AI infrastructure company evaluates its project portfolio.
Listed on Crusoe’s careers site · Apply there ↗
Director, Revenue Accounting
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $230,000 – $300,000
Anthropic is hiring a Director of Revenue Accounting to lead revenue recognition, accounts receivable, and month-end close operations for a fast-growing AI company. This role suits someone with deep technical accounting expertise and leadership experience who can manage complex ASC 606 compliance, AR processes, and mentor a growing team.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Staff Corporate Security Engineer
Crusoe
San Francisco, CA · $210,000 – $255,000
Crusoe is seeking a senior security architect to design and implement zero-trust, identity-based security systems protecting corporate infrastructure, SaaS platforms, and emerging AI workloads. This role suits experienced security engineers ready to move from tactical tool management to strategic system design at a fast-growing AI infrastructure company.
Listed on Crusoe’s careers site · Apply there ↗
Research Engineer, Economic Research Data Platform
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $320,000 – $405,000
This role builds and maintains data infrastructure for Anthropic's research into how AI affects economic activity, creating pipelines that turn raw usage data into datasets for studying AI adoption's impacts on jobs and regions. It suits engineers who've shipped data systems in production and enjoy working across technical and non-technical teams to tackle ambiguous problems at scale.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Senior Systems Engineer - IAM
Crusoe
Full-time · San Francisco, CA · $165,000 – $200,000
Crusoe seeks a hands-on Senior Systems Engineer to build and optimize their global IT infrastructure with a focus on identity and access management. This role combines Okta expertise with automation and system integration work to support a rapidly growing AI infrastructure company.
Listed on Crusoe’s careers site · Apply there ↗
Research Scientist/Engineer, Biological Safety
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $300,000 – $405,000
A researcher or engineer combining molecular biology expertise with machine learning to design safety systems that prevent frontier AI models from enabling biological harm while remaining useful to legitimate life scientists. This suits someone with deep knowledge of modern biology and scientific programming who wants to apply that expertise to AI safety evaluation and classifier development.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Automated Testing Engineer, Compute
Crusoe
Full-time · San Francisco, CA · $172,500 – $210,000
This role involves designing and maintaining automated testing frameworks for large-scale GPU clusters, with a focus on validating interconnect performance, distributed workload scaling, and multi-node stability in virtualized environments. It suits engineers with deep systems knowledge who enjoy working on low-level infrastructure challenges in a fast-moving AI compute company.
Listed on Crusoe’s careers site · Apply there ↗
Staff+ Software Engineer, Cybersecurity Products
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $405,000 – $485,000
A software engineer role building Claude Security, Anthropic's cybersecurity product suite. You'll work across the full stack from prototype to production, balancing research insights with customer needs to ship features that matter.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Senior Staff Software Engineer, Managed Orchestration
Crusoe
Full-time · San Francisco, CA · $237,600 – $288,000
Senior Staff Software Engineer leading the design and scaling of Crusoe's cloud infrastructure orchestration platform, managing Kubernetes clusters and establishing technical standards across multiple teams. This role suits experienced systems engineers who want to combine deep expertise in distributed systems with strategic leadership on high-impact infrastructure initiatives.
Listed on Crusoe’s careers site · Apply there ↗
Senior Business Systems Analyst, Finance Systems
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $205,000 – $270,000
This role leads the design and implementation of Workday Financials at Anthropic, managing the financial data model, chart of accounts, and analytics solutions as the company scales toward public company readiness. It suits someone with deep Workday expertise who can bridge finance requirements and technical implementation.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Staff Software Engineer, Systems Engineering Focus
Crusoe
Full-time · San Francisco, CA · $210,000 – $255,000
Crusoe seeks a systems-focused staff engineer to design and operate customer-facing managed services on their AI infrastructure platform, with particular responsibility for lightweight agent software deployed directly on customer systems. You'll balance building new features end-to-end with deep technical authority over edge computing architecture, Linux instrumentation, and cross-team collaboration.
Listed on Crusoe’s careers site · Apply there ↗
Research Scientist, Interpretability
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $350,000 – $850,000
This role involves developing methods to understand how large language models work by analyzing their learned algorithms and building interpretability tools. It suits researchers with a strong scientific background who want to contribute to AI safety through mechanistic understanding and enjoy collaborative, experimental science.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Senior Staff Software Engineer, Storage
Crusoe
Full-time · San Francisco, CA · $240,000 – $310,000
Crusoe seeks a Senior Staff Engineer to architect and lead the long-term technical strategy for their cloud storage infrastructure, bridging high-performance hardware with globally distributed, S3-competitive object stores. This role suits someone with deep distributed systems expertise who thrives setting technical direction and solving ambiguous infrastructure challenges at scale.
Listed on Crusoe’s careers site · Apply there ↗
[Expression of Interest] Research Manager, Interpretability
Menlo Ventures Portfolio
San Francisco, CA · $350,000 – $500,000
Anthropic is seeking an experienced manager to lead their Interpretability team, overseeing researchers and engineers focused on understanding how large language models work internally. This role suits someone with a strong technical background in ML/AI and proven experience managing high-performing research teams through ambitious, exploratory work.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Staff Software Engineer, Storage
Crusoe
San Francisco, CA · $240,000 – $310,000
Crusoe is hiring a Staff-level architect to lead the technical strategy and design of their distributed storage infrastructure, which bridges high-performance NVMe hardware with S3-compatible object storage serving AI workloads. This role suits someone with deep expertise in distributed systems and performance optimization who wants to shape a multi-year technical roadmap at a pre-IPO infrastructure company.
Listed on Crusoe’s careers site · Apply there ↗
Research Engineer, Interpretability
Menlo Ventures Portfolio
Full-time · San Francisco, CA · $315,000 – $560,000
This role builds the computational infrastructure and tooling that lets researchers understand how large language models actually work internally, rather than treating them as black boxes. It's suited to experienced software engineers who want to work on AI safety through hands-on infrastructure work, enjoy translating research needs into systems, and are comfortable optimizing across the full stack from GPU kernels to user-facing tools.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗
Senior Systems Engineer
Crusoe
San Francisco, CA · $190,000 – $230,000
Crusoe seeks a senior engineer to architect agentic AI systems that automate enterprise workflows across integrated platforms like Salesforce and Slack. This role suits someone with deep AI infrastructure expertise who thrives building scalable, production-grade automation frameworks and mentoring teams through emerging AI technologies.
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Manager– Growth Sales (AI-Native)
Menlo Ventures Portfolio
San Francisco, CA · $380,000 – $450,000
Lead a sales team of 5-10 Account Executives focused on growing Anthropic's relationships with AI-native startups, with responsibility for team revenue, customer retention, and scaling commercial processes. This role suits experienced enterprise sales managers who understand the startup ecosystem and want to build high-performing teams in the AI space.
Listed on Menlo Ventures Portfolio’s careers site · Apply there ↗