Registered Nurse jobs in South Dakota

Veterans Health Administration

Full-time · Sioux Falls, SD · $63,446 – $114,610

This VA health system role coordinates restorative nursing programs for veterans in rehabilitation and extended care settings, working with multidisciplinary teams to help patients regain independence and function. The position combines direct nursing practice with program development, staff education, and evidence-based practice improvement across a network of care providers.

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Indian Health Service

Full-time · Pine Ridge, SD · $73,426 – $109,678

This is a pediatric nursing position in a clinic setting on the Pine Ridge Indian Reservation, South Dakota, providing direct care to children and families while supporting a multidisciplinary healthcare team. The role suits registered nurses at various experience levels from entry through senior, with federal employment benefits and a required service agreement.

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Veterans Health Administration

Full-time · Sioux Falls, SD · $63,446 – $114,610

This role combines clinical nursing expertise with health information systems to identify and mitigate risks within electronic health records at a VA facility. The position suits nurses interested in patient safety, informatics, and improving care delivery through systems-level work rather than bedside care.

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Veterans Health Administration

Full-time · Hot Springs, SD · $71,638 – $134,624

The VA is hiring a registered nurse for a residential mental health program serving Veterans with psychiatric and substance use challenges. You'll deliver recovery-focused care, manage medications, coordinate treatment across an interdisciplinary team, and help Veterans build stability and move toward discharge.

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