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AeroVironment

Computational Scientist – Microbial Metabolic Modeling and Simulation

AeroVironment

WPAFB · full time

$88,500 – $135,000

Listed on AeroVironment’s own careers site. You apply with them directly — we never stand between you and the employer.

What this role is

This role develops computational models to optimize microbial strains for bioproduction, working closely with laboratory scientists to translate simulations into real experiments and back. It suits someone with a PhD in bioengineering or related field who has hands-on experience with metabolic modeling tools and wants to bridge the gap between computational predictions and wet-lab validation.

Our summary, not AeroVironment’s wording. The full posting is on their site.

Skills this role names

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What they ask for

Required

  • PhD in Bioengineering, Chemical Engineering, Computational Biology, Bioinformatics, Biochemistry, Systems Biology, or related field (or M.S. with 2+ years experience)
  • U.S. Citizenship
  • Research experience designing and optimizing microbial metabolic networks using constraint-based modeling
  • Demonstrated collaboration between computational modeling and experimental validation of strains
  • Applied metabolic engineering to microbial hosts such as E. coli, Corynebacterium, or yeast
  • Peer-reviewed publications and dissertation work in metabolic engineering and computational modeling
  • Proficiency in constraint-based metabolic modeling with COBRA toolbox in Python or MATLAB

Nice to have

  • Knowledge of dynamic flux balance analysis (dFBA) or kinetic metabolic pathway modeling
  • Understanding of molecular biology techniques for strain engineering including CRISPR/Cas9 and Gibson Assembly
  • Experience with high-throughput scripting, Python, R, or MATLAB automation and pipeline workflows
  • Familiarity with bioreactor operation modes (batch, fed-batch, continuous) and bioprocess parameters
  • Experience integrating transcriptomics, proteomics, and metabolomics data into metabolic models
  • Knowledge of commercial bioprocess applications and scale-up from lab to pilot-scale bioreactors
  • Prior wet-lab experience in microbial strain construction

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