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Merck

Associate Director, Technical Operations - Small Molecule Drug Substance

Merck

Elkton, VA · full time · Senior

$142,400 – $224,100

Listed on Merck’s own careers site. You apply with them directly — we never stand between you and the employer.

What this role is

Lead technical operations for small molecule drug manufacturing at a newly built U.S. site, overseeing process scale-up, technology transfer, and commercial production of active pharmaceutical ingredients. Suited to experienced pharmaceutical process engineers seeking to drive operational excellence and build manufacturing capability from startup through commercialization.

Our summary, not Merck’s wording. The full posting is on their site.

What they ask for

Required

  • Degree in Chemistry, Chemical Engineering, or related discipline
  • 10+ years in API process development and/or manufacturing
  • Strong background in process chemistry and scale-up
  • Strong background in process, equipment, and cleaning validation
  • Working knowledge of cGMP manufacturing operations
  • Working knowledge of regulatory expectations and inspection readiness
  • Experience with deviation management and investigations
  • Experience with electronic batch records and process systems
  • Analytical and problem-solving skills
  • Ability to work across cross-functional teams

Nice to have

  • Exposure to capital projects, CQV, and facility startup
  • Leadership experience with technical teams

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