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Merck

Senior Scientist, Antibody Discovery

Merck

South San Francisco, CA · full time · Senior

$131,400 – $206,800

Listed on Merck’s own careers site. You apply with them directly — we never stand between you and the employer.

What this role is

A hands-on laboratory scientist will lead antibody discovery campaigns using single-cell technologies and 10x Genomics workflows, designing high-throughput screening strategies and advancing candidates toward clinical development. This role suits experienced immunologists or molecular biologists who thrive in fast-paced environments and want to drive impact across multidisciplinary teams in drug discovery.

Our summary, not Merck’s wording. The full posting is on their site.

Skills this role names

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What they ask for

Required

  • Bachelor's degree with 7+ years, Master's with 4+ years, or Ph.D. in Biology, Biochemistry or related field
  • Hands-on expertise with 10x Genomics Single Cell 5' V(D)J workflow for antigen-specific antibody isolation
  • Strong laboratory skills in cell culture, molecular biology, high-throughput screening, assay development, and flow cytometry
  • Significant hands-on experience in antibody discovery using in vivo immunization and single B-cell screening approaches
  • Ability to communicate and collaborate effectively across multidisciplinary teams
  • Track record managing multiple projects in fast-paced, deadline-driven environments
  • External scientific visibility through publications, presentations, or community engagement

Nice to have

  • Experience with next-generation sequencing approaches and data interpretation in antibody discovery workflows
  • Experience managing antibody discovery campaigns

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