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Merck

Principal Scientist, Upstream Process Development

Merck

Rahway, NJ · full time · Senior

$173,200 – $272,600

Listed on Merck’s own careers site. You apply with them directly — we never stand between you and the employer.

What this role is

A leadership role in biopharmaceutical process development where you'll direct the creation of cell culture manufacturing processes from early development through commercial launch. This suits experienced bioprocess scientists ready to mentor teams and drive innovation across a pipeline of diverse therapeutic programs.

Our summary, not Merck’s wording. The full posting is on their site.

Skills this role names

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What they ask for

Required

  • PhD in Chemical Engineering, Bioengineering, Biochemistry or related field with 6+ years industry experience, or Master's with 8+ years industry experience
  • Proven track record in upstream process and technology development with scientific publications and presentations
  • Hands-on experience with CHO fed-batch cell culture and bioreactors at multiple scales
  • Working knowledge of cell culture media, CHO cell biology, metabolism, and CFD
  • Ability to direct planning, execution, analysis and documentation of cell culture process development
  • Experience with late-stage commercial process development and process characterization
  • Knowledge of biologics CMC development cycle
  • Demonstrated ability to develop and mentor junior scientists
  • Ability to work in matrixed teams with internal and external partners

Nice to have

  • Experience with intensified inoculum and perfusion process development
  • Experience with high-throughput microbioreactor systems and advanced in situ analytics
  • Expertise in media and solution chemistry
  • Background in data science approaches such as metabolic flux analysis, omics, or machine learning applied to cell culture
  • Experience leading cross-functional program development teams

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