# Computational Scientist – Microbial Metabolic Modeling and Simulation

Hiring organization: [AeroVironment](https://career.thegoodapps.co/organizations/aerovironment)

Canonical page: https://career.thegoodapps.co/jobs/d50aad69-4e87-415e-a01b-9d8cb2085885

Listed on AeroVironment's own careers site. Applications go to them directly.

- Employment type: full time
- Location: WPAFB
- Salary: 88500 – 135000 USD per year

## Summary

This role develops computational models to optimize microbial strains for bioproduction, working closely with laboratory scientists to translate simulations into real experiments and back. It suits someone with a PhD in bioengineering or related field who has hands-on experience with metabolic modeling tools and wants to bridge the gap between computational predictions and wet-lab validation.

_Our summary, not AeroVironment's wording._

## Skills named

MATLAB, Python

## Required

- PhD in Bioengineering, Chemical Engineering, Computational Biology, Bioinformatics, Biochemistry, Systems Biology, or related field (or M.S. with 2+ years experience)
- U.S. Citizenship
- Research experience designing and optimizing microbial metabolic networks using constraint-based modeling
- Demonstrated collaboration between computational modeling and experimental validation of strains
- Applied metabolic engineering to microbial hosts such as E. coli, Corynebacterium, or yeast
- Peer-reviewed publications and dissertation work in metabolic engineering and computational modeling
- Proficiency in constraint-based metabolic modeling with COBRA toolbox in Python or MATLAB

## Nice to have

- Knowledge of dynamic flux balance analysis (dFBA) or kinetic metabolic pathway modeling
- Understanding of molecular biology techniques for strain engineering including CRISPR/Cas9 and Gibson Assembly
- Experience with high-throughput scripting, Python, R, or MATLAB automation and pipeline workflows
- Familiarity with bioreactor operation modes (batch, fed-batch, continuous) and bioprocess parameters
- Experience integrating transcriptomics, proteomics, and metabolomics data into metabolic models
- Knowledge of commercial bioprocess applications and scale-up from lab to pilot-scale bioreactors
- Prior wet-lab experience in microbial strain construction

Apply on AeroVironment's site: https://avav.wd1.myworkdayjobs.com/en-US/AVAV/job/WPAFB/Computational-Scientist---Microbial-Metabolic-Modeling-and-Simulation_8019