# Principal Scientist, Upstream Process Development

Hiring organization: [Merck](https://career.thegoodapps.co/organizations/merck)

Canonical page: https://career.thegoodapps.co/jobs/7f4adc5a-c9d7-49b5-8ce8-046bd522bcb6

Listed on Merck's own careers site. Applications go to them directly.

- Employment type: full time
- Seniority: Senior
- Location: Rahway, NJ
- Salary: 173200 – 272600 USD per year

## Summary

A leadership role in biopharmaceutical process development where you'll direct the creation of cell culture manufacturing processes from early development through commercial launch. This suits experienced bioprocess scientists ready to mentor teams and drive innovation across a pipeline of diverse therapeutic programs.

_Our summary, not Merck's wording._

## Skills named

Computational Fluid Dynamics (CFD), Finite Element Analysis (FEA), Machine Learning

## Required

- PhD in Chemical Engineering, Bioengineering, Biochemistry or related field with 6+ years industry experience, or Master's with 8+ years industry experience
- Proven track record in upstream process and technology development with scientific publications and presentations
- Hands-on experience with CHO fed-batch cell culture and bioreactors at multiple scales
- Working knowledge of cell culture media, CHO cell biology, metabolism, and CFD
- Ability to direct planning, execution, analysis and documentation of cell culture process development
- Experience with late-stage commercial process development and process characterization
- Knowledge of biologics CMC development cycle
- Demonstrated ability to develop and mentor junior scientists
- Ability to work in matrixed teams with internal and external partners

## Nice to have

- Experience with intensified inoculum and perfusion process development
- Experience with high-throughput microbioreactor systems and advanced in situ analytics
- Expertise in media and solution chemistry
- Background in data science approaches such as metabolic flux analysis, omics, or machine learning applied to cell culture
- Experience leading cross-functional program development teams

Apply on Merck's site: https://msd.wd5.myworkdayjobs.com/en-US/SearchJobs/job/USA---New-Jersey---Rahway/Principal-Scientist--Upstream-Process-Development_R399271-1