# Principal Scientist, Lab Platform Disruptive Technologies

Hiring organization: [Merck](https://career.thegoodapps.co/organizations/merck)

Canonical page: https://career.thegoodapps.co/jobs/1ad9c393-a4b6-46d7-8e5c-8a5f8b99affa

Listed on Merck's own careers site. Applications go to them directly.

- Employment type: full time
- Seniority: Principal
- Location: Cambridge, MA
- Salary: 194100 – 305600 USD per year

## Summary

Lead the development and deployment of next-generation experimental technologies for biologics discovery, translating emerging methods into scalable internal capabilities that accelerate drug programs through high-throughput quantitative data generation. This role suits an experienced scientist with deep expertise in assay development and lab-based methods who can bridge hands-on technical work with team leadership and cross-functional collaboration.

_Our summary, not Merck's wording._

## Skills named

Automation

## Required

- PhD in Biochemistry, Bioengineering, Chemical Biology or related field with 7+ years industry experience (or MS/BS with 12+ years)
- Experience developing large-scale, high-throughput quantitative experimental methods for biologics discovery
- Track record of translating published or externally developed methods into demonstrable internal value
- Leadership and team management experience
- Deep hands-on expertise in quantitative pooled binding assays, high-throughput endpoint assays, lab-on-chip, or microfluidics
- Strong biochemistry and biophysical characterization knowledge
- Cross-functional project leadership experience
- Ability to collaborate across reporting lines with protein engineers and data scientists

## Nice to have

- Understanding of protein structure-function relationships
- Experience with in vitro transcription and translation
- Background in biophysical protein characterization
- Therapeutic high-throughput developability assessment
- Automation and scalable experimental workflow design
- Experience with generative AI and machine learning workflows

Apply on Merck's site: https://msd.wd5.myworkdayjobs.com/en-US/SearchJobs/job/USA---Massachusetts---Cambridge-320-Bent-Street/Principal-Scientist--Lab-Platform-Disruptive-Technologies_R407843-1